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Read this first! / Login Problem Workaround
« Last post by The Professor on October 05, 2017, 03:32:25 AM »
A forum software update created a login problem for our users. I have modified the landing page so that users wishing to login will be directed to the full login page instead of using the broken embedded form.

Sorry if you were inconvenienced.
Art / Re: Martial art
« Last post by Unbeliever on June 07, 2017, 02:43:07 PM »
I doubt there really is a "best" one. It depends on the person, I think, as to which is best for them. I prefer the soft arts, like judo, for example, as opposed to the hard ones, like karate.

Chin na is not, by itself, a martial art, but is a part of all martial arts - the art of grappling.
Art / Re: Martial art
« Last post by Summitt on June 06, 2017, 10:20:45 PM »
Martial arts truly are the arts. Which on is the best do you think?

As human lifespan increases, a greater fraction of the population is suffering from age-related cognitive impairments, making it important to elucidate a means to combat the effects of aging1, 2. Here we report that exposure of an aged animal to young blood can counteract and reverse pre-existing effects of brain aging at the molecular, structural, functional and cognitive level. Genome-wide microarray analysis of heterochronic parabionts—in which circulatory systems of young and aged animals are connected—identified synaptic plasticity–related transcriptional changes in the hippocampus of aged mice. Dendritic spine density of mature neurons increased and synaptic plasticity improved in the hippocampus of aged heterochronic parabionts. At the cognitive level, systemic administration of young blood plasma into aged mice improved age-related cognitive impairments in both contextual fear conditioning and spatial learning and memory. Structural and cognitive enhancements elicited by exposure to young blood are mediated, in part, by activation of the cyclic AMP response element binding protein (Creb) in the aged hippocampus. Our data indicate that exposure of aged mice to young blood late in life is capable of rejuvenating synaptic plasticity and improving cognitive function.
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